Sheikh Mohammad Fazle Akbar
Toshiba General Hospital, Japan
Title: Therapeutic vaccines against chronic hepatitis-B virus and related complications
Biography
Biography: Sheikh Mohammad Fazle Akbar
Abstract
With the advent of novel insights about pathogenesis of chronic hepatitis-B (CHB) and realizing the limitations of commercially available antiviral drugs for CHB, new, novel and evidence-based therapeutic approaches using hepatitis-B virus (HBV)-related antigens (Therapeutic Vaccines) have been accomplished in CHB patients during last two decades. Therapeutic vaccines for CHB patients have been composed of different HBV-related antigens with different forms of adjuvants and stimulants. Also, therapeutic vaccines have been administered in CHB patients by different routes and for variable durations. The safety profiles of therapeutic vaccines and their efficacies would be discussed for designing acceptable regimen of this new and novel mode of immune therapy for CHB patients.