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Jean-Francois Fonteneau


Jean-Francois Fonteneau

University of Nantes, France

Biography

Jean-François Fonteneau has done his PhD degree from Nantes University, France, in 1999. During his thesis training in the INSERM Laboratory of Pr Francine Jotereau, Nantes, France, he studied human CD8+ T lymphocytes response against melanoma and how to induce such response. He joined Dr. Nina Bhardwaj’s Group in Dr. Ralph Steinman Laboratory as a Post-doctoral Fellow at Rockefeller University, New York, USA, from 1999 to 2003, where he studied human dendritic cells (DC) biology, notably cross-presentation of viral and tumor antigens and interactions between virus, myeloid DC and plasmacytoid DC. In 2009, he joined Dr. Marc Gregoire's Laboratory, INSERM U892, Nantes, to study attenuated measles virus as an oncolytic virus for oncolytic immunotherapy of pleural mesothelioma to induce immunogenic cell death of tumor cells to initiate or increase the antitumor immune response.

Abstract

Abstract : Exploiting defects of type I interferon response in tumor cells for oncolytic immunotherapy with attenuated measles virus